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. 2025 Nov 12;26:188. doi: 10.1186/s40360-025-01045-4

Table 2.

Mean ± SEM BMI (g/cm2) and organ weight (g) of adult female Sprague Dawley rats treated with different doses of PYR

Treatments Parameters

BMI

(g/cm2)

Ovary

Weight

Uterine

Weight

Kidney

Weight

Liver

weight

Heart

weight

Control 0.14 ± 0.067 0.12 ± 0.01 0.31 ± 0.07 0.49 ± 0.03 5.79 ± 0.30 0.66 ± 0.04

G1

(62 mg/kg)

0.12 ± 0.018 0.09 ± 0.01a*** 0.43 ± 0.09 0.67 ± 0.07a* 6.27 ± 0.26 0.76 ± 0.04

G2

(124 mg/kg)

0.13 ± 0.062 0.08 ± 0.01a*** 0.48 ± 0.09 0.68 ± 0.06a* 7.14 ± 0.43a* 0.75 ± 0.04

G3

(186 mg/kg)

0.12 ± 0.053 0.07 ± 0.01a*** 0.57 ± 0.08a* 0.70 ± 0.04a* 8.82 ± 0.51a***b*** 0.80 ± 0.03a*

a= (value compared to control), b = (value compared to G1), * (p < 0.05), ** (p < 0.01), *** (p < 0.001)