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. 2025 Nov 12;26:188. doi: 10.1186/s40360-025-01045-4

Table 4.

Mean ± SEM of lipid profile, protein concentration and reproductive hormone profile of adult female Sprague Dawley rats were treated with different doses of PYR

Treatments Biochemical parameters
Total Protein
concentration
Total
Cholesterol (mmol/L)
Total glyceride
Level (mmol/L)
High-density lipids Cholesterol (mg/dL) Progesterone (ng/ml) Estradiol (ng/ml) Cortisol (ng/ml)
Control 5.63 ± 0.36 53.07 ± 4.25 74.1 ± 4.25 65.53 ± 2.55 77.30 ± 4.87 50.71 ± 2.23 84.8 ± 8.40
G1(62 mg/kg) 5.72 ± 0.38 62.83 ± 4.77 78.91 ± 4.24b** 63.66 ± 1.13b*** 74.96 ± 2.21 32.42 ± 3.71 a* 39.8 ± 2.70 a***
G2 (124 mg/kg) 6.29 ± 0.16 59.53 ± 4.62 86.15 ± 4.05b** 55.71 ± 4.02a* 63.14 ± 3.74 a* 29.66 ± 3.04 a** 33.6 ± 2.44 a***
G3 (186 mg/kg) 6.29 ± 0.28 67.09 ± 2.91s* 93.99 ± 3.93a* 43.72 ± 3.9a*** 62.98 ± 4.18 a* 27.90 ± 3.39 a** 31.6 ± 3.47 a***

a = (value compared to control), b = (value compared to G3), * (p < 0.05), ** (p < 0.01), *** (p < 0.001)

n = 6 per group