Table 5.

Percentage of rats in each estrous cycle stage following PYR Treatment. Data represents the percentage of animals within a group observed in a given stage on each sampling day

Group / Stage	Day 1	Day 7	Day 14	Day 21	Day 28
Control
Proestrus	33.3%	16.7%	0%	50.0%	16.7%
Estrus	50.0%	66.7%	83.3%	33.3%	66.7%
Metestrus	16.7%	16.7%	16.7%	16.7%	16.7%
Diestrus	0%	0%	0%	0%	0%
G1 (62 mg/kg)
Proestrus	0%	0%	0%	0%	0%
Estrus	33.3%	16.7%	0%	0%	0%
Metestrus	66.7%	83.3%	100%	100%	83.3%
Diestrus	0%	0%	0%	0%	16.7%
G2 (124 mg/kg)
Proestrus	0%	0%	0%	0%	0%
Estrus	0%	16.7%	0%	0%	0%
Metestrus	16.7%	50.0%	33.3%	33.3%	16.7%
Diestrus	83.3%	33.3%	66.7%	66.7%	83.3%
G3 (186 mg/kg)
Proestrus	0%	0%	0%	0%	0%
Estrus	0%	0%	0%	0%	0%
Metestrus	16.7%	0%	33.3%	33.3%	16.7%
Diestrus	83.3%	100%	66.7%	66.7%	83.3%