Table 6.
Histomorphometric analysis of ovarian follicles and structures in rats treated with PYR
| Group | Healthy Antral Follicles | Atretic Follicles | Corpora Lutea | Cysts | Empty Space Area (%) |
|---|---|---|---|---|---|
| Control | 8.5 ± 0.8a | 1.2 ± 0.4a | 6.8 ± 0.6 | 0.0 ± 0.0a | 2.1 ± 0.5a |
| G1 (62 mg/kg) | 5.8 ± 0.7a, b | 3.5 ± 0.6b | 7.5 ± 0.7 | 0.3 ± 0.2a | 5.8 ± 1.1a, b |
| G2 (124 mg/kg) | 3.3 ± 0.5b, c | 6.2 ± 0.8c | 8.2 ± 0.9 | 1.5 ± 0.3b | 11.4 ± 1.8b |
| G3 (186 mg/kg) | 1.7 ± 0.4c | 8.8 ± 0.9d | 8.7 ± 0.8 | 2.8 ± 0.4c | 18.9 ± 2.3c |
Values represent Mean ± SEM per ovarian section. Different superscript letters (a, b, c) within a column denote significant differences (p < 0.05) as determined by one-way ANOVA followed by Tukey’s test