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| DNA methyltransferase | Methylation (nM CH3/h) |
|---|---|
| hDNMT1 | 15 ± 0.45 |
| hDNMT3a | 0.4 ± 0.04 |
| hDNMT3b | 1.25 ± 0.04 |
| hDNMT3a + hDNMT3b | 1.8 ± 0.03 |
| hDNMT1 + hDNMT3a | 18 ± 0.1 |
| hDNMT1 + hDNMT3b | 28 ± 0.8 |
| hDNMT1 + hDNMT3a + hDNMT3b | 26.1 ± 0.06 |
Each methylation reaction was performed twice in duplicate. Final methyl group incorporation was calculated after deduction of the background value.
