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American Journal of Cancer Research logoLink to American Journal of Cancer Research
. 2025 Oct 25;15(10):4608–4609. doi: 10.62347/ZCMW4495

A low dose of AZD8055 enhances radiosensitivity of nasopharyngeal carcinoma cells by activating autophagy and apoptosis

Lihong Chang 1,*, Zizhen Huang 1,*, Shuaixiang Li 1,*, Zhouzhou Yao 1, Hongwei Bao 1, Zhiyuan Wang 1, Xia Li 1, Xiaohong Chen 1, Jiancong Huang 1, Gehua Zhang 1
PMCID: PMC12616171  PMID: 41244109

This article contained a few mistakes in Figure 5B and 5D, which have no influence on the final findings and conclusions. In Figure 5B, the Acridine Orange staining of CNE1 treated with AZD8055 and CNE2 treated with AZD8055 were inadvertently partially overlapped, and the Acridine Orange staining of CNE1 treated with 4 Gy and CNE2 treated with 4 Gy were inadvertently partially overlapped, because of the wrong-usage of the images of CNE1 during the assembly of the figures for publication. In Figure 5D, the TEM image of CNE2 treated with IR was inadvertently a copy of the image of CNE1 control, and the TEM image of CNE1 treated with IR was wrong used, during the assembly of the figures. We regret for these unintentional mistakes caused by careless operation in the process of data acquisition and image layout, and apologize for any inconvenience or misunderstanding that these errors may have caused. The corrected Figure 5 is shown as follows.

Figure 5.

Figure 5

AZD8055 enhanced autophagy. A. Confocal microscopy images of CNE1 and CNE2 cells after immunofluorescence staining for LC3 (red) protein after 2 days of treatment with AZD8055 and 4 Gy IR; the number of cells with more than 15 dots representing LC3 labeling was determined. B. Acridine Orange staining of CNE1 and CNE2 cells treated with AZD8055 and 4 Gy IR. C. Western blot images of p-mTOR, mTOR, p62 and LC3 protein expression assessed in CNE1 and CNE2 cells treated with AZD8055 and 4 Gy IR. D. The ultrastructure of cells with different treatments were analyzed by TEM (23000×). N. Nucleus, *autophaosomes, #amphisomes.


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