Fig. 1. Characterization of the p53–STK15 interaction in yeast. Left column: GAL4 DNA-binding domain (amino acids 1–147) hybrids. Middle column: GAL4 activation domain (amino acids 768–881) hybrids. The STK15 fragment fused to GAL4 activation domain is indicated on the right of the diagrams. The relative positions of the Aurora box and kinase domains of STK15 are also depicted. Right column: yeast colony color after transformation; the relative color is in parentheses. No colony indicates that no yeast colony was observed after incubation for a standard period of time.