Figure 2.

SETD1A regulates tumorigenesis

(a) Serial bioluminescence imaging of shNT and shSETD1A-MDA-MB-231 tumor-bearing mice. Luciferase-expressing MDAMB-231 cells infected with shNT or shSETD1A lentiviruses were inoculated into the mammary fat pads of immunocompromised mice. (b) Tumor growth was assessed using bioluminescence imaging. (c) GFP-labeled MDA-MB-231 cells infected with shNT or shSETD1A lentiviruses were inoculated into the mammary fat pads of immunocompromised mice. Liver metastases were identified by tracking GFP signals using a stereomicroscope.