Rep/RepA indicates the two alternative expression products of the replication-associated protein gene. Solid lines represent specific protein–protein interactions [14,16–18,21,22], dotted lines represent specific protein–DNA interactions [14,16,19–21], and dashed lines indicate CP-DNA interactions of unknown specificity [18–20,22]. For protein–DNA interactions, arrows point from the protein component to the DNA component of the interactions. Rep interacts with the LIR at three distinct sites [14]. CP and Rep form oligomers (solid circular arrows) [14,22]. Although CP must interact with the rest of the genome (including its own gene) during encapsidation, the sequence specificity of these interactions is unknown.