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. 2025 Oct 6;11(4):753–763. doi: 10.1007/s41030-025-00319-w
Why carry out this study?
There is a call for immediate action against global warming in health care.
Pressurized metered-dose inhalers (pMDIs), widely used in the treatment of patients with asthma or chronic obstructive pulmonary disease (COPD), have a 20-40-fold higher carbon footprint compared to propellant-free dry powder inhalers (DPIs).
This post hoc analysis assessed the effect of switching from a pressurized metered-dose inhaler (pMDI) to the budesonide–formoterol Easyhaler DPI on disease control and the carbon footprint of the treatment.
What was learned from the study?
The results show improvements in clinical outcome parameters among patients with asthma or COPD when they switched from pMDI to DPI.
The amount of estimated kg CO2e emissions per year for maintenance treatment was 97.0% lower for the DPI than for pMDI.
The results strengthen the evidence on decreased environmental impact of inhaler treatment with DPIs without compromising the disease control.