TABLE 1.

Summary of aptamer B40 binding data

Construct bound	Maximala		Relativeb
	−CD4	+CD4	In comparison to full-length gp120	Fold increase in presence of CD4
Full-length gp120	330	412	1	1.2
Core+ V3	55	235	0.2	4.3
Core	101	184	0.3	1.8

^aMaximal binding of the aptamer, expressed in response units, at 180 s. −CD4, in the absence of sCD4; +CD4, in the presence of sCD4.

^bRelative binding of the aptamer, expressed as a unitless ratio to show the comparison with binding to full-length gp120 and fold increase in aptamer binding in the presence of CD4.