TABLE 3.
Anti-HBe monoclonal antibodies recognize WHeAga
| Anti-HBe MAb | Level of binding (OD492 or titer)
|
|
|---|---|---|
| HBeAg | WHeAg | |
| 904 | 0.80 | 0.55 |
| 905 | 0.58 | 0.23 |
| 420 | 0.70 | 0.34 |
| 422 | 0.97 | 0.58 |
| 426 | 0.53 | 0.17 |
| BA8-E | 1:2,560 | 1:10,240 |
| BA11-E | 1:2,560 | 1:1,280 |
| CE1-E | 1:2,560 | 1:2,560 |
A panel of HBeAg-specific MAbs (904, 905, 420, 422, 426) at 0.1 μg/ml were screened for binding to solid-phase HBeAg and WHeAg (50 ng/well). Results are depicted as OD492 results minus background binding on blank wells. MAbs BA8-E, BA11-E, and CE1-E were tested by end point dilution.