FIG. 4.

Mutational patterns in HPV-52 variants. The two top rows indicate the genomic position in the published HPV-52 reference sequence and the corresponding nucleotides. Positions 7387 to 8391 could not be detected by resequencing the original reference clone or in any variants, leading to the corrected sequence of the HPV-52 reference clone in the third row (refer. cor.). In the following rows, nucleotide exchanges are shown by letters, deletions relative to the reference clone by a hyphen, and an insert in one variant (between positions 7701 and 7702) by an open square in variants that lack this insert.