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. Author manuscript; available in PMC: 2006 Oct 1.
Published in final edited form as: J Nutr. 2005 Oct;135(10):2337–2342. doi: 10.1093/jn/135.10.2337

Fig. 4.

Fig. 4

Immunocytochemistry experiments are consistent with a rapid and transient decrease in K12-biotinylated histone H4 in JAr cell nuclei in response to treatment with etoposide. Panel A: Staining of biotinylation of K12 in histone H4 and cellular compartments in etoposide-free JAr cells: a = staining of nuclei using DAPI; b = staining of K12-biotinylation of histone H4, using a site-specific antibody; c = staining of cytoplasmic compartment using rhodamine phalloidin; d = merged image. Panel B: Time course of K12-biotinylation in histone H4 after addition of etoposide to culture media.