Table 1.
Composition of Control, low dose of the inhibitor (LDI), high dose of the inhibitor (HDI) and atorvastatin diets
Components | Control % | LDI % | HDI % | Atorvastatin % |
Soybean protein | 22.5 | 22.5 | 22.5 | 22.5 |
Methionine | 0.5 | 0.5 | 0.5 | 0.5 |
Sucrose | 25 | 25 | 25 | 25 |
Corn Starch | 15 | 15 | 15 | 15 |
Fat mix1 | 15.1 | 15.1 | 15.1 | 15.1 |
Cellulose | 10 | 10 | 10 | 10 |
Guar gum | 2.5 | 2.5 | 2.5 | 2.5 |
Mineral Mix2 | 8.2 | 8.2 | 8.2 | 8.2 |
Vitamin Mix2 | 1.1 | 1.1 | 1.1 | 1.1 |
Cholesterol | 0.08 | 0.08 | 0.08 | 0.08 |
JTT-130 | 0 | 0.0005 | 0.0015 | 0 |
Statin | 0 | 0 | 0 | 0.05 |
1 Fat mix for the diet contains olive oil-palm kernel oil-safflower oil (1:2:1.8), high in lauric and myristic acids.
2 Mineral and vitamin mix adjusted to meet NRC requirements for guinea pigs. Detailed composition of the vitamin and mineral mix has been reported elsewhere (Fernandez et al. 1992b).