Table 2.
Plasma total cholesterol (TC), triglycerides (TG), VLDL-C, LDL-C and HDL-C of guinea pigs fed a control diet, low dose MTPi (LDI), high dose MTPi (HDI) or atorvastatin
| Diets | TC | TG | VLDL-C | LDL-C | HDL-C |
| (mg/dL) | |||||
| Control (10) | 146.9 ± 42.2a | 135.8 ± 118.9a | 8.1 ± 5.5ab | 123.9 ± 43.5a | 13.6 ± 4.5a |
| LDI (10) | 116.9 ± 29.7b | 66.7 ± 29.6b | 3.7 ± 3.0a | 93.3 ± 26.2b | 18.5 ± 8.0a |
| HDI (9) | 116.1 ± 23.3b | 74.3 ± 31.7b | 9.0 ± 8.6b | 90.5 ± 28.8b | 15.6 ± 7.1a |
| Atorvastatin (9) | 76.5 ± 29.8c | 49.4 ± 32.2c | 2.9 ± 2.6a | 59.4 ± 29.3c | 14.1 ± 5.6a |
1Data are presented as mean ± SD for the number of guinea pigs indicated in parenthesis. Numbers in a column with different superscripts are considered significantly different (P < 0.01) as determined by one way ANOVA and LSD as a post-hoc test