Table 2.
Subclones | t11-az-4 (-/M) | t11-az-8 (+/M)a | t11-az-9 (+/M)a | t11-az-10 (+/M) |
TIMP-, methylated (-/M) | 10 | 10 | 15 | 3 |
TIMP+, Methylated (+/M) | 0 | 2a | 2a | 13 |
TIMP+, Unmethylated (+/U) | 0 | 0 | 0 | 1 |
aExpression in these branches was initially weak and became silent after time in culture. ELK1 expression was initially retained in one of the t11-az-9 TIMP1+ clones but was not analyzed after TIMP1 expression was lost. The expression of ZNF41/157 was not examined in these subclones.