Table 2.

Utility Gains Adjusted for Adverse Effects

	VAS	SEM	SG	SEM
Baseline	0.519	0.00725	0.712	0.00578
12 weeks	0.570*	0.00676	0.751†	0.00560
24 weeks	0.583*	0.00668	0.762†	0.00542
36 weeks	0.594*	0.00658	0.768†	0.00551
50 weeks	0.591*	0.00668	0.766†	0.00554
Endpoint	0.583*	0.00647	0.763†	0.00552

VAS indicates visual analog scale; SEM, standard error of the mean; SG, standard gamble.

*P < 0.001 versus baseline visual-analog-scale measurement (Wilcoxon signed rank test).

^†P < 0.001 versus baseline standard-gamble measurement (Wilcoxon signed rank test).