Table 2.
Reference values for B lymphocyte subsets and dendritic cells for children aged 0 − 12 years
| 0–2 years (median: 1.1) n = 23 | 2–4 years (median: 3.4) n = 14 | 4–6 years (median: 4.9) n = 16 | 6–12 years (median: 8.1) n = 15 | |
|---|---|---|---|---|
| Naive B lymphocytes (%) | 83 (75 − 89) | 73 (66 − 79) | 66 (51 − 74) | 56 (45 − 66) |
| Memory B lymphocytes (%) | 13 (9 − 23) | 25 (17 − 32) | 29 (23 − 45) | 41 (29 − 53) |
| Non-switched memory B, nsmB (%) | 10 (7 − 15) | 14 (9 − 21) | 15 (11 − 23) | 20 (12 − 27) |
| Switched memory B, smB (%) | 2 (1 − 3) | 5 (4 − 10) | 10 (6 − 24) | 14 (8 − 21) |
| CD21lowCD38low activated B (%) | 6 (3 − 8) | 8 (5 − 11) | 10 (6 − 13) | 10 (6 − 20) |
| CD19+CD38highIgMhigh transitional B (%) | 12 (8 − 17) | 9 (7 − 15) | 6 (3 − 11) | 4 (3 − 6) |
| Plasmablasts (%) | 0.6 (0.2 − 1.4) | 0.3 (0.2 − 2.0) | 1 (0.3 − 2.8) | 0.6 (0.2 − 1.6) |
| Plasmacytoid dendritic cells, pDC (%) | 0.18 (0.06 − 0.32) | 0.18 (0.08 − 0.38) | 0.2 (0.09 − 0.37) | 0.18 (0.11 − 0.48) |
| Myeloid dendritic cells, mDC (%) | 0.08 (0.02 − 0.16) | 0.08 (0.02 − 0.18) | 0.15 (0.07 − 0.29) | 0.1 (0.03 − 0.2) |
Percentages are shown as median and percentile range (P10 − P90). B cell subsets are shown as % of CD19+ B cells, and dendritic cells as % of peripheral blood leucocytes