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. 2025 Nov 6;6:1614433. doi: 10.3389/froh.2025.1614433

Table 4.

Correlations between biomarkers and demographic data within the periodontitis group (stage I + II, stage III + IV).

Variables Irisin Visfatin IL-6
r p-value r p-value r p-value
Stage I + II Irisin (pg/ml)
Visfatin (pg/ml) −0.705 0.015
IL-6 (pg/ml) −0.118 0.727 −0.635 0.033
PLI% −0.636 0.035 0.868 0.000 0.638 0.034
BOP% −0.623 0.040 0.699 0.016 0.684 0.020
PPD (mm) −0.625 0.039 0.781 0.004 0.672 0.023
CAL (mm) −0.614 0.044 0.763 0.006 0.674 0.022
Stage III + IV Irisin (pg/ml)
visfatin (pg/ml) −0.635 0.003
IL-6 (pg/ml) −0.465 0.044 0.546 0.015
PLI% −0.821 0.000 0.717 0.000 0.568 0.008 S
BOP% −0.727 0.000 0.604 0.006 0.534 0.018 S
PPD (mm) −0.679 0.001 0.654 0.002 0.595 0.007 S
CAL (mm) −0.486 0.034 0.486 0.034 0.707 0.000 S

(Pearson correlation coefficients (r values).