Table 2. Antifungal minimum inhibitory concentrations of 13 Candidozyma auris isolates according to European Committee on Antimicrobial Susceptibility Testing guidelines^a, Czechia, August 2022–December 2024.

			Antifungal minimum inhibitory concentrations (mg/L)
Patient	Isolate ID	Clade	AMB	FLU	ITC	VOR	POS	ISA	AFG	MFG	ERG11	FKS1
1	C39/22	III	0.5	64	0.125	1	0.03	0.06	0.06	0.03	VF125AL	WT
2	C654/24	III	0.5	64	0.125	0.25	0.03	0.03	0.06	0.06	VF125AL	WT
3	C864/24	IV	1	8	0.06	0.06	0.03	0.03	0.06	0.06	WT	WT
4	C909/24	I	1	≥ 64	0.125	1	0.06	0.06	2	1	Y132F	S639P
4	C958/24	I	0.5	≥ 64	0.25	1	0.03	0.06	2	2	Y132F	S639P
5	C985/24	IV	1	8	0.06	0.03	0.016	0.03	0.03	0.03	WT	WT
5	C986/24	IV	1	4	0.06	0.03	0.03	0.03	0.03	0.06	WT	WT
5	C1083/24	IV	1	64	0.25	0.25	0.125	0.25	0.06	0.06	WT	WT
5	C1084/24	IV	1	64	0.125	0.25	0.125	0.125	0.06	0.06	WT	WT
6	C1230/24	I	1	≥ 64	0.25	0.5	0.06	0.125	0.06	0.06	Y132F	WT
6	C1231/24	I	1	≥ 64	0.25	1	0.06	0.125	0.03	0.06	Y132F	WT
7	C1321/24	I	0.5	≥ 64	0.25	0.5	0.125	0.125	0.06	0.03	Y132F	WT
8	C1167/24	IV	1	64	0.25	0.5	0.25	0.5	0.06	0.06	WT	WT
Range antifungals			0.5–1	4–≥ 64	0.06–0.25	0.03–1	0.016–0.25	0.03–0.5	0.03–2	0.03–2	NA	NA

AMB: amphotericin B; AFG: anidulafungin; FLU: fluconazole; ID: identification; ISA: isavuconazole; ITC: itraconazole; MFG: micafungin; NA: not applicable; POS: posaconazole; VOR: voriconazole; WT: wild type.

^a European Committee on Antimicrobial Susceptibility Testing (EUCAST) Eukaryotic definitive broth microdilution test method (E.DEF) version 7.4.

Clades were determined by short tandem repeat genotyping.