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. 2025 Oct 22;14(6):1899–1914. doi: 10.1007/s40122-025-00784-w

Table 2.

Responder rates for different efficacy parameters and their combinations in episodic migraine

Efficacy parameter Responder rate Significance vs. highest responder rate
Monthly migraine days reduced by ≥ 50% 50.3% p < 0.00001
HIT-6 score reduced by ≥ 5 points 67.5% p < 0.00001
MIDAS score reduced by ≥ 30% 69.5% p < 0.00001
HIT-6 score or monthly migraine days 75.1% p = 0.0231
MIDAS score or monthly migraine days 78.7%

n.s

p = 0.1512

MIDAS score or HIT-6 score 83.3%

n.s

p = 0.7836

MIDAS or HIT-6 or monthly migraine days 84.7%