Table 1.
The baseline information of seven cardiac vascular disorders, retina layers, and biomarkers. Bold values indicate statistically significant differences (p < 0.05).
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| PHENOTYPE | CONTROL | CHD | p | HF | p | MI | p | STROKE | p | CA | p | AF | p | CVD TOTAL | p |
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| N | 35 | 25 | 11 | 21 | 10 | 12 | 10 | 89 | |||||||
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| AGE | 67.2 ± 9.7 | 65.2 ± 8.6 | 0.408 | 70.4 ± 7.3 | 0.331 | 65.2 ± 9.6 | 0.450 | 66.4 ± 11.7 | 0.821 | 66.4 ± 8.9 | 0.807 | 63.0 ± 5.8 | 0.199 | 65.9 ± 8.9 | 0.541 |
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| GENDER | 0.825 | 0.703 | 1.000 | 0.872 | 0.943 | 0.872 | 0.806 | ||||||||
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| Male | 15 (42.9%) | 10 (40.0%) | 4 (36.4%) | 9 (42.9%) | 4 (40.0%) | 5 (41.7%) | 4 (40.0%) | 36 (40.4%) | |||||||
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| Female | 20 (57.1%) | 15 (60.0%) | 7 (63.6%) | 12 (57.1%) | 6 (60.0%) | 7 (58.3%) | 6 (60.0%) | 53 (59.6%) | |||||||
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| BP | 0.452 | 0.179 | 0.143 | 0.648 | 0.107 | 0.026 | 0.043 | ||||||||
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| No | 16 (45.7%) | 9 (36.0%) | 3 (27.3%) | 6 (28.6%) | 4 (40.0%) | 3 (25.0%) | 2 (20.0%) | 27 (30.3%) | |||||||
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| Yes | 19 (54.3%) | 16 (64.0%) | 8 (72.7%) | 15 (71.4%) | 6 (60.0%) | 9 (75.0%) | 8 (80.0%) | 62 (69.7%) | |||||||
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| ALCOHOL | 0.042 | 0.048 | 0.338 | 0.186 | 0.035 | 0.776 | 0.676 | ||||||||
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| No | 21 (60.0%) | 11 (44.0%) | 5 (45.5%) | 11 (52.4%) | 5 (50.0%) | 5 (41.7%) | 6 (60.0%) | 43 (48.3%) | |||||||
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| Yes | 14 (40.0%) | 14(56.0%) | 6 (55.5%) | 10 (47.6%) | 5 (50.0%) | 7(58.3%) | 4(40.0%) | 46(51.7%) | |||||||
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| SMOKE | 0.759 | 0.786 | 0.862 | 0.315 | 0.038 | 0.287 | 0.150 | ||||||||
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| No | 17 (48.6%) | 11 (44.0%) | 5 (45.5%) | 10 (47.6%) | 6 (60.0%) | 8 (66.7%) | 5 (50.0%) | 45 (50.6%) | |||||||
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| Yes | 18 (51.4%) | 14 (56.0%) | 6 (18.2%) | 11(52.4%) | 4(40.0%) | 4(33.3%) | 5 (50.0%) | 44(49.4%) | |||||||
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| RNFL | 102.7 ± 7.0 | 90.4 ± 9.6 | <0.001 | 100.6 ± 8.7 | 0.134 | 88.6 ± 12.8 | <0.001 | 89.7 ± 8.0 | <0.001 | 98.5 ± 5.1 | 0.066 | 100.1 ± 13.2 | 0.417 | 93.3 ± 11.1 | <0.001 |
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| GCIPL | 85.8 ± 4.7 | 85.3 ± 5.0 | 0.723 | 85.1 ± 8.3 | 0.438 | 85.0 ± 4.4 | 0.445 | 85.3 ± 3.6 | 0.511 | 84.5 ± 4.7 | 0.422 | 85.1 ± 5.2 | 0.698 | 85.1 ± 5.1 | 0.275 |
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| INL | 40.4 ± 3.7 | 40.8 ± 3.8 | 0.736 | 40.1 ± 4.9 | 0.786 | 44.5 ± 5.0 | 0.002 | 41.1 ± 5.4 | 0.671 | 40.6 ± 3.8 | 0.902 | 40.7 ± 3.9 | 0.841 | 41.6 ± 4.6 | 0.153 |
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| OPONL | 89.7 ± 6.4 | 89.5 ± 5.8 | 0.870 | 90.1 ± 6.3 | 0.908 | 90.1 ± 6.8 | 0.819 | 90.7 ± 6.8 | 0.725 | 89.8 ± 6.1 | 0.932 | 88.6 ± 6.0 | 0.615 | 89.8 ± 6.1 | 0.978 |
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| PR-IS/OS | 65.2 ± 2.6 | 69.1 ± 3.2 | <0.001 | 64.4 ± 3.0 | 0.288 | 70.0 ± 3.7 | <0.001 | 65.6 ± 4.1 | 0.773 | 64.7 ± 3.3 | 0.263 | 67.8 ± 3.9 | 0.017 | 67.6 ± 4.1 | 0.002 |
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| RPE-BM | 23.2 ± 2.3 | 22.2 ± 2.8 | 0.105 | 22.3 ± 2.4 | 0.292 | 20.5 ± 2.6 | <0.001 | 21.2 ± 3.1 | 0.015 | 23.0 ± 3.1 | 0.883 | 22.5 ± 3.5 | 0.434 | 21.8 ± 2.9 | 0.010 |
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| INNER | 228.9 ± 9.3 | 216.4 ± 10.5 | <0.001 | 225.8 ± 17.9 | 0.131 | 218.1 ± 14.4 | 0.006 | 216.1 ± 10.1 | <0.001 | 223.6 ± 7.9 | 0.109 | 225.9 ± 16.1 | 0.462 | 220.0 ± 13.2 | <0.001 |
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| OUTER | 178.2 ± 7.1 | 180.8 ± 6.6 | 0.159 | 176.7 ± 7.3 | 0.527 | 180.7 ± 7.6 | 0.189 | 177.5 ± 9.5 | 0.460 | 177.5 ± 7.8 | 0.723 | 178.9 ± 8.6 | 0.787 | 179.2 ± 7.6 | 0.526 |
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| ALT | 24.7 ± 17.3 | 21.2 ± 7.8 | 0.341 | 22.4 ± 7.8 | 0.718 | 22.9 ± 12.3 | 0.624 | 21.9 ± 12.2 | 0.967 | 25.2 ± 13.8 | 0.678 | 23.0 ± 12.8 | 0.773 | 22.5 ± 10.7 | 0.872 |
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| AST | 24.8 ± 13.7 | 21.4 ± 6.2 | 0.252 | 21.4 ± 4.2 | 0.877 | 22.2 ± 8.0 | 0.793 | 22.4 ± 12.0 | 0.642 | 23.0 ± 9.7 | 0.845 | 23.1 ± 8.1 | 0.711 | 22.1 ± 7.8 | 0.711 |
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| GGT | 29.1 ± 10.6 | 30.8 ± 17.8 | 0.656 | 31.7 ± 13.3 | 0.827 | 32.5 ± 20.6 | 0.741 | 31.1 ± 49.0 | 0.005 | 32.1 ± 18.4 | 0.971 | 30.1 ± 15.1 | 0.816 | 31.4 ± 22.7 | 0.377 |
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| TBIL | 9.5 ± 4.6 | 10.4 ± 5.0 | 0.474 | 10.4 ± 8.7 | 0.652 | 11.7 ± 6.1 | 0.253 | 9.8 ± 3.5 | 0.672 | 13.2 ± 7.1 | 0.133 | 7.9 ± 4.0 | 0.315 | 10.7 ± 5.9 | 0.505 |
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| ALB | 44.7 ± 2.3 | 44.7 ± 2.5 | 0.962 | 44.5 ± 2.4 | 0.767 | 44.8 ± 2.8 | 0.953 | 44.1 ± 2.8 | 0.428 | 44.3 ± 3.3 | 0.971 | 43.6 ± 2.4 | 0.193 | 44.5 ± 2.6 | 0.569 |
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| CREA | 75.2 ± 15.4 | 71.6 ± 13.7 | 0.365 | 79.1 ± 22.4 | 0.877 | 78.6 ± 19.7 | 0.531 | 67.2 ± 15.5 | 0.263 | 76.6 ± 20.1 | 0.591 | 89.6 ± 31.6 | 0.050 | 76.4 ± 20.3 | 0.918 |
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| UREA | 6.0 ± 1.7 | 6.1 ± 1.6 | 0.799 | 6.1 ± 1.5 | 0.757 | 6.1 ± 2.1 | 0.859 | 5.9 ± 1.5 | 0.806 | 6.6 ± 2.9 | 0.942 | 7.2 ± 2.9 | 0.107 | 6.3 ± 2.1 | 0.665 |
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| UA | 303.4 ± 63.7 | 315.2 ± 69.5 | 0.499 | 308.5 ± 101.7 | 0.908 | 321.9 ± 88.3 | 0.526 | 316.0 ± 45.5 | 0.495 | 307.7 ± 52.4 | 1.000 | 330.2 ± 72.8 | 0.261 | 316.7 ± 73.5 | 0.361 |
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| TC | 5.1 ± 1.1 | 5.8 ± 1.4 | 0.032 | 5.6 ± 1.6 | 0.149 | 5.8 ± 1.4 | 0.077 | 5.8 ± 1.0 | 0.101 | 5.9 ± 1.5 | 0.127 | 5.4 ± 1.2 | 0.437 | 5.7 ± 1.3 | 0.015 |
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| TG | 1.4 ± 0.7 | 1.6 ± 1.0 | 0.365 | 1.5 ± 0.5 | 0.511 | 1.7 ± 0.8 | 0.094 | 1.5 ± 0.5 | 0.287 | 1.7 ± 0.3 | 0.019 | 1.8 ± 0.8 | 0.147 | 1.6 ± 0.7 | 0.047 |
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| HDL_C | 1.2 ± 0.4 | 1.0 ± 0.3 | 0.018 | 1.3 ± 0.3 | 0.519 | 1.1 ± 0.2 | 0.243 | 1.0 ± 0.3 | 0.275 | 1.1 ± 0.3 | 0.550 | 1.1 ± 0.4 | 0.613 | 1.1 ± 0.3 | 0.169 |
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| LDL_C | 2.0 ± 0.8 | 3.1 ± 0.7 | <0.001 | 2.5 ± 0.5 | 0.039 | 2.4 ± 0.6 | 0.074 | 2.7 ± 0.5 | 0.006 | 2.4 ± 0.5 | 0.097 | 2.5 ± 0.5 | 0.081 | 2.7 ± 0.6 | <0.001 |
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| Lp(a) | 150.2 ± 187.6 | 201.1 ± 257.1 | 0.379 | 308.6 ± 274.5 | 0.092 | 179.2 ± 111.2 | 0.050 | 177.3 ± 139.9 | 0.072 | 230.6 ± 247.4 | 0.414 | 166.5 ± 130.8 | 0.799 | 206.6 ± 206.5 | 0.062 |
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| APOA | 1.1 ± 0.3 | 1.0 ± 0.3 | 0.068 | 1.0 ± 0.2 | 0.455 | 1.0 ± 0.3 | 0.326 | 0.9 ± 0.3 | 0.020 | 1.1 ± 0.3 | 0.942 | 1.0 ± 0.2 | 0.119 | 1.0 ± 0.3 | 0.055 |
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| APOB | 0.8 ± 0.2 | 0.9 ± 0.3 | 0.081 | 0.9 ± 0.3 | 0.381 | 0.9 ± 0.3 | 0.101 | 1.1 ± 0.2 | 0.002 | 0.8 ± 0.1 | 0.200 | 0.8 ± 0.2 | 0.969 | 0.9 ± 0.3 | 0.038 |
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| GLU | 5.6 ± 1.0 | 5.2 ± 0.8 | 0.179 | 5.3 ± 0.5 | 0.220 | 5.5 ± 0.9 | 0.846 | 5.7 ± 1.2 | 0.521 | 6.2 ± 2.5 | 1.000 | 5.8 ± 1.4 | 0.580 | 5.6 ± 1.3 | 0.507 |
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| ALP | 80.7 ± 21.0 | 78.2 ± 17.4 | 0.636 | 82.1 ± 13.6 | 0.562 | 80.8 ± 29.9 | 0.594 | 80.4 ± 21.4 | 0.935 | 78.3 ± 13.9 | 0.903 | 79.5 ± 25.0 | 0.881 | 79.7 ± 21.0 | 0.879 |
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