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. 2025 Nov 21;20(1):104. doi: 10.5334/gh.1493

Table 1.

The baseline information of seven cardiac vascular disorders, retina layers, and biomarkers. Bold values indicate statistically significant differences (p < 0.05).


PHENOTYPE CONTROL CHD p HF p MI p STROKE p CA p AF p CVD TOTAL p

N 35 25 11 21 10 12 10 89

AGE 67.2 ± 9.7 65.2 ± 8.6 0.408 70.4 ± 7.3 0.331 65.2 ± 9.6 0.450 66.4 ± 11.7 0.821 66.4 ± 8.9 0.807 63.0 ± 5.8 0.199 65.9 ± 8.9 0.541

GENDER 0.825 0.703 1.000 0.872 0.943 0.872 0.806

Male 15 (42.9%) 10 (40.0%) 4 (36.4%) 9 (42.9%) 4 (40.0%) 5 (41.7%) 4 (40.0%) 36 (40.4%)

Female 20 (57.1%) 15 (60.0%) 7 (63.6%) 12 (57.1%) 6 (60.0%) 7 (58.3%) 6 (60.0%) 53 (59.6%)

BP 0.452 0.179 0.143 0.648 0.107 0.026 0.043

No 16 (45.7%) 9 (36.0%) 3 (27.3%) 6 (28.6%) 4 (40.0%) 3 (25.0%) 2 (20.0%) 27 (30.3%)

Yes 19 (54.3%) 16 (64.0%) 8 (72.7%) 15 (71.4%) 6 (60.0%) 9 (75.0%) 8 (80.0%) 62 (69.7%)

ALCOHOL 0.042 0.048 0.338 0.186 0.035 0.776 0.676

No 21 (60.0%) 11 (44.0%) 5 (45.5%) 11 (52.4%) 5 (50.0%) 5 (41.7%) 6 (60.0%) 43 (48.3%)

Yes 14 (40.0%) 14(56.0%) 6 (55.5%) 10 (47.6%) 5 (50.0%) 7(58.3%) 4(40.0%) 46(51.7%)

SMOKE 0.759 0.786 0.862 0.315 0.038 0.287 0.150

No 17 (48.6%) 11 (44.0%) 5 (45.5%) 10 (47.6%) 6 (60.0%) 8 (66.7%) 5 (50.0%) 45 (50.6%)

Yes 18 (51.4%) 14 (56.0%) 6 (18.2%) 11(52.4%) 4(40.0%) 4(33.3%) 5 (50.0%) 44(49.4%)

RNFL 102.7 ± 7.0 90.4 ± 9.6 <0.001 100.6 ± 8.7 0.134 88.6 ± 12.8 <0.001 89.7 ± 8.0 <0.001 98.5 ± 5.1 0.066 100.1 ± 13.2 0.417 93.3 ± 11.1 <0.001

GCIPL 85.8 ± 4.7 85.3 ± 5.0 0.723 85.1 ± 8.3 0.438 85.0 ± 4.4 0.445 85.3 ± 3.6 0.511 84.5 ± 4.7 0.422 85.1 ± 5.2 0.698 85.1 ± 5.1 0.275

INL 40.4 ± 3.7 40.8 ± 3.8 0.736 40.1 ± 4.9 0.786 44.5 ± 5.0 0.002 41.1 ± 5.4 0.671 40.6 ± 3.8 0.902 40.7 ± 3.9 0.841 41.6 ± 4.6 0.153

OPONL 89.7 ± 6.4 89.5 ± 5.8 0.870 90.1 ± 6.3 0.908 90.1 ± 6.8 0.819 90.7 ± 6.8 0.725 89.8 ± 6.1 0.932 88.6 ± 6.0 0.615 89.8 ± 6.1 0.978

PR-IS/OS 65.2 ± 2.6 69.1 ± 3.2 <0.001 64.4 ± 3.0 0.288 70.0 ± 3.7 <0.001 65.6 ± 4.1 0.773 64.7 ± 3.3 0.263 67.8 ± 3.9 0.017 67.6 ± 4.1 0.002

RPE-BM 23.2 ± 2.3 22.2 ± 2.8 0.105 22.3 ± 2.4 0.292 20.5 ± 2.6 <0.001 21.2 ± 3.1 0.015 23.0 ± 3.1 0.883 22.5 ± 3.5 0.434 21.8 ± 2.9 0.010

INNER 228.9 ± 9.3 216.4 ± 10.5 <0.001 225.8 ± 17.9 0.131 218.1 ± 14.4 0.006 216.1 ± 10.1 <0.001 223.6 ± 7.9 0.109 225.9 ± 16.1 0.462 220.0 ± 13.2 <0.001

OUTER 178.2 ± 7.1 180.8 ± 6.6 0.159 176.7 ± 7.3 0.527 180.7 ± 7.6 0.189 177.5 ± 9.5 0.460 177.5 ± 7.8 0.723 178.9 ± 8.6 0.787 179.2 ± 7.6 0.526

ALT 24.7 ± 17.3 21.2 ± 7.8 0.341 22.4 ± 7.8 0.718 22.9 ± 12.3 0.624 21.9 ± 12.2 0.967 25.2 ± 13.8 0.678 23.0 ± 12.8 0.773 22.5 ± 10.7 0.872

AST 24.8 ± 13.7 21.4 ± 6.2 0.252 21.4 ± 4.2 0.877 22.2 ± 8.0 0.793 22.4 ± 12.0 0.642 23.0 ± 9.7 0.845 23.1 ± 8.1 0.711 22.1 ± 7.8 0.711

GGT 29.1 ± 10.6 30.8 ± 17.8 0.656 31.7 ± 13.3 0.827 32.5 ± 20.6 0.741 31.1 ± 49.0 0.005 32.1 ± 18.4 0.971 30.1 ± 15.1 0.816 31.4 ± 22.7 0.377

TBIL 9.5 ± 4.6 10.4 ± 5.0 0.474 10.4 ± 8.7 0.652 11.7 ± 6.1 0.253 9.8 ± 3.5 0.672 13.2 ± 7.1 0.133 7.9 ± 4.0 0.315 10.7 ± 5.9 0.505

ALB 44.7 ± 2.3 44.7 ± 2.5 0.962 44.5 ± 2.4 0.767 44.8 ± 2.8 0.953 44.1 ± 2.8 0.428 44.3 ± 3.3 0.971 43.6 ± 2.4 0.193 44.5 ± 2.6 0.569

CREA 75.2 ± 15.4 71.6 ± 13.7 0.365 79.1 ± 22.4 0.877 78.6 ± 19.7 0.531 67.2 ± 15.5 0.263 76.6 ± 20.1 0.591 89.6 ± 31.6 0.050 76.4 ± 20.3 0.918

UREA 6.0 ± 1.7 6.1 ± 1.6 0.799 6.1 ± 1.5 0.757 6.1 ± 2.1 0.859 5.9 ± 1.5 0.806 6.6 ± 2.9 0.942 7.2 ± 2.9 0.107 6.3 ± 2.1 0.665

UA 303.4 ± 63.7 315.2 ± 69.5 0.499 308.5 ± 101.7 0.908 321.9 ± 88.3 0.526 316.0 ± 45.5 0.495 307.7 ± 52.4 1.000 330.2 ± 72.8 0.261 316.7 ± 73.5 0.361

TC 5.1 ± 1.1 5.8 ± 1.4 0.032 5.6 ± 1.6 0.149 5.8 ± 1.4 0.077 5.8 ± 1.0 0.101 5.9 ± 1.5 0.127 5.4 ± 1.2 0.437 5.7 ± 1.3 0.015

TG 1.4 ± 0.7 1.6 ± 1.0 0.365 1.5 ± 0.5 0.511 1.7 ± 0.8 0.094 1.5 ± 0.5 0.287 1.7 ± 0.3 0.019 1.8 ± 0.8 0.147 1.6 ± 0.7 0.047

HDL_C 1.2 ± 0.4 1.0 ± 0.3 0.018 1.3 ± 0.3 0.519 1.1 ± 0.2 0.243 1.0 ± 0.3 0.275 1.1 ± 0.3 0.550 1.1 ± 0.4 0.613 1.1 ± 0.3 0.169

LDL_C 2.0 ± 0.8 3.1 ± 0.7 <0.001 2.5 ± 0.5 0.039 2.4 ± 0.6 0.074 2.7 ± 0.5 0.006 2.4 ± 0.5 0.097 2.5 ± 0.5 0.081 2.7 ± 0.6 <0.001

Lp(a) 150.2 ± 187.6 201.1 ± 257.1 0.379 308.6 ± 274.5 0.092 179.2 ± 111.2 0.050 177.3 ± 139.9 0.072 230.6 ± 247.4 0.414 166.5 ± 130.8 0.799 206.6 ± 206.5 0.062

APOA 1.1 ± 0.3 1.0 ± 0.3 0.068 1.0 ± 0.2 0.455 1.0 ± 0.3 0.326 0.9 ± 0.3 0.020 1.1 ± 0.3 0.942 1.0 ± 0.2 0.119 1.0 ± 0.3 0.055

APOB 0.8 ± 0.2 0.9 ± 0.3 0.081 0.9 ± 0.3 0.381 0.9 ± 0.3 0.101 1.1 ± 0.2 0.002 0.8 ± 0.1 0.200 0.8 ± 0.2 0.969 0.9 ± 0.3 0.038

GLU 5.6 ± 1.0 5.2 ± 0.8 0.179 5.3 ± 0.5 0.220 5.5 ± 0.9 0.846 5.7 ± 1.2 0.521 6.2 ± 2.5 1.000 5.8 ± 1.4 0.580 5.6 ± 1.3 0.507

ALP 80.7 ± 21.0 78.2 ± 17.4 0.636 82.1 ± 13.6 0.562 80.8 ± 29.9 0.594 80.4 ± 21.4 0.935 78.3 ± 13.9 0.903 79.5 ± 25.0 0.881 79.7 ± 21.0 0.879