Skip to main content
[Preprint]. 2025 Nov 5:2025.11.03.686369. [Version 1] doi: 10.1101/2025.11.03.686369

Figure 3. Specc1lΔCCD2CCD2 display decreased SPECC1L and F-actin expression in the pericentriolar region.

Figure 3.

A-B. Mouse embryonic fibroblasts (MEFs) from WT(A) and Specc1ΔCCD2CCD2 (B) were stained for SPECC1L (white), F-actin (red), acetylated-α-tubulin (green) and DAPI. C-D. Quantification of a 1x1x1 μm cubic volume of interest (VOI) for SPECC1L (C) and F-actin (D) showed a significant reduction for both in ΔCCD2 mutant cells (****<0.0001, * 0.0138, N=3, n=15 cilia, Scale bar represents 2μm, Error bars represent Mean ± standard deviation (SD) ).