Figure 5. Primary cilia length shortening correlates with phenotypic severity.
Quantification of primary cilia length was performed on palate mesenchyme tissue from three (E) 13.5 embryos with WT (n=250), Thm1aln+ (n=75), Specc1lΔCCD2/+ (n=150), Specc1lΔCCD2/+;Thm1−/+ (n=90), Specc1lΔCCD2/ΔCCD2 (n=150), Specc1lΔEx4/ΔEx4 (n=290), Specc1lΔEx4/ΔEx4;Thm1aln/+ (n=50), and Thm1aln/aln (n=50) genotypes (** <0.0078, **** <0.0001, Error bars represent 95% CI).
