Skip to main content
[Preprint]. 2025 Nov 5:2025.11.03.686369. [Version 1] doi: 10.1101/2025.11.03.686369

Figure 6. Cytoskeletal feedback in Thm1 mutant cells.

Figure 6.

A-B. Mouse embryonic fibroblasts (MEFs) from WT(A) and Thm1aln/aln (B) embryos were stained with F-actin (red) and DAPI (blue). A’-B’. 2x zoom of the boxed regions of cells shown in A-B. C. Quantification of mean gray value for actin/cell from 5 experiments (** <0.0051). D. Quantification of cell circularity ratio (width/length) from 3 experiments (n=45/genotype, ****<0.0001). E. Quantification of primary cilia length in WT and Thm1aln/aln MEFs treated with vehicle (DMSO) and Latrunculin B (LatB) from 3 experiments (n= 50, *<0.0234, **<0.0071, ****<0.0001, Scale bar represents 2μm, Error bars represent 95% CI).