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[Preprint]. 2025 Nov 5:2025.11.03.686369. [Version 1] doi: 10.1101/2025.11.03.686369

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Figure 7. — A-C. Schematic representation of mesenchymal cell, highlighting the actin cytoskeleton and primary cilium. A. Wild-type cell with normal distribution of actin cytoskeleton and primary cilia in homeostasis. B. Specc1l^{ΔCCD2/ΔCCD2} cell with abnormal distribution of the actin cytoskeleton including a halo around the nucleus. Distribution of the actin cytoskeleton in the cytoplasm has increased inhibition on ciliogenesis. C. Thm1^aln/aln cell showing decreased intensity of the F-actin cytoskeleton and decreased inhibition on the primary cilium, resulting from the IFT-A defect.