Table 3.

Treatment related adverse events (n=24).

Adverse events	Any grade, n (%)	Grade 3/4. n (%)
Any adverse event	22 (92)	10 (42)
Fatigue	9 (38)	2 (8)
Rash	5 (21)	1 (4)
Anorexia	4 (17)	0
Hypertension	12 (50)	4 (17)
Proteinuria	4 (17)	0
leukopenia	6 (25)	1 (4)
Neutropenia	3 (13)	1 (4)
Thrombocytopenia	10 (42)	0
AST elevation	8 (33)	2 (8)
ALT elevation	4 (17)	1 (4)
Hyperbilirubinemia	5 (21)	0
Infusion related reaction	1 (4)	0
Palmar-plantar arerythrodysesthesia syndrome	1 (4)	0
Gastric ulcer	2 (8)	0
Adrenal insufficiency	4 (17)	0
Immune-mediated pneumonitis	1 (4)	0
Immune-mediated colitis	0	1 (4)
Immune-mediated dermatitis	5 (21)	2 (8)
Immune-mediated hepatitis	1 (4)	1 (4)