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. 2025 Nov 12;13(4):265. doi: 10.3390/medsci13040265
ACC acetyl-CoA carboxylase
AER adverse event report
AEs adverse events
ALT alanine transaminase
AST aspartate transaminase
APRI aspartate aminotransferase to platelet ratio index
AUDIT-C alcohol use disorders-concise score
BMI body mass index
CKD chronic kidney disease
CRP c-reactive protein
CT computed tomography
CV cardiovascular
DPP-4 dipeptidyl-peptidase-4
EMA European Medical Agency
FAERS FDA Adverse Events Reporting System
FDA Food and drug administration
FXR farnesoid X receptor
GLP-1 RA glucagon-like peptide 1 receptor agonist
GI gastrointestinal
GIP gastrointestinal peptide
HbA1c glycated hemoglobin
HU hounsfield unit
kPa kilopascal
LFC liver fat content
LSM liver stiffness measurement
MALO major adverse liver outcome
MASH metabolic dysfunction-associated steatohepatitis
ML machine learning
MRE magnetic resonance elastography
MRI-PDFF magnetic resonance imaging-proton density fat fraction
NAFLD nonalcoholic fatty liver disease
NAION non-arteritic anterior ischemic optic neuropathy
NASH nonalcoholic steatohepatitis
NITs Non-invasive tests
OTTES observational target trial emulation study
OD once daily
OW once weekly
PRAC Pharmacovigilance Risk Assessment Committee
RCT randomized controlled trial
sc subcutaneous
SELECT semaglutide effects on cardiovascular outcomes in people with overweight or obesity
SH steatohepatitis
SLD steatotic liver disease
STOP semaglutide treatment effect on coronary atherosclerosis progression
SUSTAIN semaglutide unabated sustainability in treatment of type 2 diabetes
T2D type 2 diabetes