Skip to main content
. 2025 Nov 17;2025:4623346. doi: 10.1155/humu/4623346

Table 4.

IL-10 genotype and allele frequency for patients with GDM.

IL-10 loci Control group ( N = 280) GDM group ( N = 160) OR (95% CI) a p a
n Percentage (%) n Percentage (%)
−592 C/A
 CC 78 27.9 38 23.8 1.00REF
 CA 112 40.0 76 47.5 1.39 (0.86–2.37) 0.180
 AA 90 32.1 46 28.7 0.91 (0.53–1.56) 0.738
 C 268 47.9 152 47.5 1.00REF
 A 292 52.1 118 52.5 1.01 (0.77–1.34) 0.919
−1082 G/A
 GG 102 36.4 40 25.0 1.00REF
 GA 114 40.7 77 48.1 1.72 (1.24–2.39) 0.001
 AA 64 22.9 43 26.9 1.71 (1.18–2.50) 0.005
 G 318 56.8 157 49.1 1.00REF
 A 242 43.2 163 50.9 1.36 (1.12–2.66) 0.002
−819 T/C
 TT 162 57.8 100 62.5 1.00REF
 TC 110 39.3 54 33.8 1.80 (0.45–1.42) 0.530
 CC 8 2.9 6 3.7 1.22 (0.26–5.66) 0.881
 T 434 77.5 254 79.4 1.00REF
 C 126 22.5 66 20.6 1.90 (0.56–1.44) 0.735

Note: The bolded data are significant in terms of statistics. “REF” represents “reference group.”

Abbreviations: CI, confidential index; GDM, gestational diabetes mellitus; OR, odds ratio.

aAdjusted for sex and age by logistic regression model.