Skip to main content
. Author manuscript; available in PMC: 2026 Jul 23.
Published in final edited form as: J Am Acad Child Adolesc Psychiatry. 2025 Jul 23;65(7):917–928. doi: 10.1016/j.jaac.2025.07.421

Figure 2. Changes in functional network topological metrics following 12-week psychostimulant treatment.

Figure 2.

Note: Network topological changes are separately shown for (A) global efficiency, (B) characteristic path length, (C) left SPG nodal degree, and (D) right amygdala nodal efficiency. Left SPG and right amygdala localization in axial, sagittal and coronal views are illustrated. Values are group mean ± SEM. P-values for the group × time interaction are presented, and asterisks indicate significant within-group baseline-endpoint changes. HR-MAS = high-risk youth treated with mixed amphetamine salts; LR-MAS = low-risk youth treated with mixed amphetamine salts. SEM = standard error of the mean. SPG = superior parietal gyrus.

*p < .05, **p < 0.01, ***p < .001.