Figure 4. Prediction of treatment responses based on baseline functional connectome.
Note: (A) Prediction performance in LR-MAS and HR-MAS groups and both groups combined presented as correlations between actual response and predicted response. (B) The most contributive edges consistently selected by the prediction model over all cross-validation folds. The size of the nodes indicates the number of connections with the region. (C) Top 10 regions contributing most to the prediction. ACC = anterior cingulate cortex; CUN = cuneus; HES = Heschl gyrus; HR-MAS = high-risk youth treated with mixed amphetamine salts; LR-MAS = low-risk youth treated with mixed amphetamine salts; mSFG = medial superior frontal gyrus; PoCG = postcentral gyrus; smOFC = superior medial orbitofrontal cortex; SOC = superior occipital cortex.
