TABLE 4.
Duplexing detection of cccDNA and rcDNA in single HBsAg-positive cellsa
| Cells with cccDNA only detected | Cells with rcDNA only detected | Cells with both cccDNA and rcDNA | Total | |
|---|---|---|---|---|
| P5 (lower SSC) | 28 (25%)a | 74 (67%)a | 8 (7%) | 110 |
| P6 (higher SSC) | 68 (78%)a | 13 (15%)a | 7 (7%) | 87 |
Chi-square value (X2) is 55.54 and P-value is 9.14 × 10−14 in comparison of the differences in the detected cccDNA only and rcDNA only containing cells between P5 and P6 populations.