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. 2025 Nov 6;99(11):e01295-25. doi: 10.1128/jvi.01295-25

TABLE 4.

Duplexing detection of cccDNA and rcDNA in single HBsAg-positive cellsa

Cells with cccDNA only detected Cells with rcDNA only detected Cells with both cccDNA and rcDNA Total
P5 (lower SSC) 28 (25%)a 74 (67%)a 8 (7%) 110
P6 (higher SSC) 68 (78%)a 13 (15%)a 7 (7%) 87
a

Chi-square value (X2) is 55.54 and P-value is 9.14 × 10−14 in comparison of the differences in the detected cccDNA only and rcDNA only containing cells between P5 and P6 populations.