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. 1966 Jan;98(1):70–77. doi: 10.1042/bj0980070

Selective degradation of thymidine and thymine deoxynucleotides

K Burton 1, W T Riley 1,*
PMCID: PMC1264796  PMID: 5938667

Abstract

1. Osmium tetroxide in dilute ammonia oxidizes various pyrimidine nucleosides at different rates. Thymidine is oxidized about 45 times as fast as deoxycytidine. The phosphate groups may be eliminated from oxidized thymine nucleotides by successive treatments with alkali and then with diphenylamine in aqueous formic acid. The reactions can be applied to the selective degradation of thymidine in oligodeoxynucleotides.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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