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. 2025 Oct 29;13(11):2656. doi: 10.3390/biomedicines13112656
2D Two-Dimensional
2D-PAGE Two-Dimensional Polyacrylamide Gel Electrophoresis
16S rRNA 16S Ribosomal Ribonucleic Acid
AAV DTR Adeno-Associated Virus Diphtheria Toxin Receptor
AI Artificial Intelligence
ASPN Asporin
ATS American Thoracic Society
BALF Bronchoalveolar Lavage Fluid
BALF-EVs Extracellular Vesicles Isolated from Bronchoalveolar Lavage Fluid
BTNL9 Butyrophilin Like 9
CCL CC-Chemokine Ligand
CCL17, 22, 25, 28 Chemokine (C-C motif) Ligands
CCL18 Chemokine (C-C motif) Ligand 18
CCD19Lu Normal Human Lung Fibroblast Cell Line
CD44 Cluster of Differentiation 44
ChIP-Seq Chromatin Immunoprecipitation Sequencing
CLIA Clinical Laboratory Improvement Amendments
COL1A1 Collagen Type I Alpha 1 Chain
COPD Chronic Obstructive Pulmonary Disease
CRP C-Reactive Protein
CyTOF Cytometry by Time of Flight
CCT6A Chaperonin Containing TCP1 Subunit 6A
DIA Data-Independent Acquisition
DIGE Differential Gel Electrophoresis
DLCO Diffusion Lung Carbon Monoxide
ECM Extracellular Matrix
ELISA Enzyme-Linked Immunosorbent Assay
ERS European Respiratory Society
ESI Electrospray Ionization
FDA Food and Drug Administration
FF Fibroblastic Foci
FFPE Formalin-Fixed Paraffin-Embedded (Tissue)
FGF Fibroblast Growth Factor
FVC Forced Vital Capacity
GC-MS Gas Chromatography–Mass Spectrometry
GREM1 Gremlin 1
HDMSE High-Definition Mass Spectrometry with Data-Dependent Acquisition
HP Haptoglobin
HPX Hemopexin
HRCT High-Resolution Computed Tomography
HRMS High-Resolution Mass Spectrometry
HSP90AA1 Heat Shock Protein 90 Alpha Family Class A Member 1
HSP90AB1 Heat Shock Protein 90 Alpha Family Class B Member 1
IIP Idiopathic Interstitial Pneumonia
IGFBP5 Insulin-Like Growth Factor Binding Protein 5
IL Interleukin
ILD Interstitial Lung Disease
IPF Idiopathic Pulmonary Fibrosis
iTRAQ Isobaric Tags for Relative and Absolute Quantitation
KL-6 Krebs von den Lungen-6
LASSO Least Absolute Shrinkage and Selection Operator
LC-MS Liquid Chromatography–Mass Spectrometry
LC-MS/MS Liquid Chromatography–Tandem Mass Spectrometry
LCP1 Lymphocyte Cytosolic Protein 1
LDHA Lactate Dehydrogenase A
LGALS7 Galectin-7
LL29, LL97A IPF-derived Human Lung Fibroblast Cell Lines
LFQ Label-Free Quantification
LTBP1 Latent Transforming Growth Factor Beta Binding Protein 1
LUM Lumican
MALDI Matrix-Assisted Laser Desorption/Ionization
MALDI-TOF MS Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry
MALDI-ToF/ToF Matrix-Assisted Laser Desorption/Ionization Time-of-Flight/Time-of-Flight Mass Spectrometry
MIF Macrophage Migration Inhibitory Factor
MIMECAN (OGN) Mimecan
MMP Matrix Metalloproteinase
MMPs Matrix Metalloproteinases
MS Mass Spectrometry
MS/MS Tandem Mass Spectrometry
MUC5B Mucin 5B
NF-kB Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells
NMR Nuclear Magnetic Resonance
OGN Mimecan
OPN Osteopontin
PC37 37-Protein Classifier
PCR Polymerase Chain Reaction
PDE4B Phosphodiesterase 4B
PLOD2 Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 2
POSTN Periostin
PPARγ Peroxisome Proliferator-Activated Receptor Gamma
PRDX2 Peroxiredoxin-2
ProCanFDL Proteomics Cancer Federated Deep Learning
PTMs Post-Translational Modifications
RNA-Seq RNA Sequencing
RCT Randomized Controlled Trial
SAA1 Serum Amyloid A1
SCGB1A1 Secretoglobin Family 1A Member 1
SCoPE Single-Cell Proteomics by Mass Spectrometry
SERPINB3 Serpin Family B Member 3
SFRP1 Secreted Frizzled-Related Protein 1
SNP Single Nucleotide Polymorphism
SOMAmer Slow-Off Rate-Modified Aptamer
SP-A Surfactant Protein A
SP-D Surfactant Protein D
SPARC Secreted Protein Acidic and Rich in Cysteine
STRING Search Tool for the Retrieval of Interacting Genes/Proteins
SSc Systemic Sclerosis
SVM Support Vector Machine
TAGLN2 Transgelin 2
TERC Telomerase RNA Component
TERT Telomerase Reverse Transcriptase
TGF-β Transforming Growth Factor Beta
Th2 T Helper Type 2
TMT Tandem Mass Tag
TNF-α Tumor Necrosis Factor Alpha
UIP Usual Interstitial Pneumonia
VEGF Vascular Endothelial Growth Factor
VOCs Volatile Organic Compounds