ACSS2	Acetyl-CoA synthetase 2
ALDOC	Aldolase c
ATP	Adenosine triphosphate
AXIN	Axis inhibition protein
BACE1	Beta-secretase 1
BTC	Biliary tract cancer
CAFs	Cancer-associated fibroblasts
CCA	Cholangiocarcinoma
CHMP1B	Charged multivesicular body protein 1B
dCCA	Distal cholangiocarcinoma
DNM1L	Dynamin 1 like
DUBs	Deubiquitinating enzymes
EGFR	Epidermal growth factor receptor
EGLN3	Prolyl 4-hydroxylase domain protein 3
ENO2	Enolase 2
ENO3	Enolase 3
ESCRT-II	Endosomal sorting complexes required for transport III
FDA	Food and drug administration
GBC	Gallbladder cancer
GCN5	General control of amino-acid synthesis 5-like 2
GPX4	Glutathione peroxidase 4
GST	Glutathione S-transferase
HCC	Hepatocellularcarcinoma
HIF1α	Hypoxia-inducible factor 1-alpha
HSP90	Heat shock protein 90
iCCA	Intrahepatic cholangiocarcinoma
IFN-β	Interferon-beta
IHC	Immunohistochemistry
IRF3	Interferon regulatory factor 3 signaling
ITCH	Itchy E3 ubiquitin protein ligase
IP	Immunoprecipitation
JAMMs	JAMM/MPN+metalloproteases
KAT2A	Lysine acetyltransferase 2A
KDM4C	lysine-specific demethylase 4C
KIF1Bβ	Kinesin family member 1B Beta isoform
KPNA2	Karyopherin subunit alpha 2
LATS2	Large tumor suppressor kinase 2
MAPK	Mitogen-activated protein kinase
MCL-1	Myeloid cell leukemia-1
MCPIPs	Monocyte chemotactic protein-induced proteins
MDA5	Melanoma differentiation-associated protein 5
MINDYs	MIU-containing novel DUB family
MIT	Microtubule-interacting and trafficking
mtDNA	Mitochondrial DNA
NF-κB	Nuclear factor kappa-light-chain-enhancer of activated B cells
NLSs	Nuclear localization sequence
OGT	O-GlcNAc transferase
OTUs	Ovarian tumor proteases
UCHs	Ubiquitin C-terminal hydrolases
PARP1	Poly (ADP-ribose) polymerase 1
pCCA	Perihilar cholangiocarcinoma
PD-L1	Programmed death-ligand 1
PDX	Patient-derived xenograft
PI3K/AKT	Phosphatidylinositol 3-kinase/protein kinase B
PKLR	Pyruvate kinase L/R
PPPDEs	Papain-like peptidases of dsRNA viruses and eukaryotes
PROTAC	Proteolysis targeting chimera
RIP1	Receptor-interacting protein 1
ROS	Reactive oxygen species
RPS16	Ribosomal protein S16
SBM	SH3-binding motifs
STING	Stimulator of interferon genes
SIRT1	Sirtuin 1
TBK1	TANK-binding kinase 1
TGF-β	Transforming growth factor-beta
TME	Tumor microenvironment
TNM	Tumor-node-metastasis
USPs	Ubiquitin-specific proteases
USP1	Ubiquitin specific peptidase 1
USP3	Ubiquitin specific peptidase 3
USP8	Ubiquitin specific peptidase 8
USP9X	Ubiquitin specific peptidase 9, X-linked
USP21	Ubiquitin specific peptidase 21
USP22	Ubiquitin specific peptidase 22
Wnt	Wingless-type
ZNF	Zinc finger protein
ZUP1	zinc finger-containing ubiquitin peptidase 1