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. 2025 Nov 14;14(22):1789. doi: 10.3390/cells14221789
TCR T cell receptor
APC Antigen-presenting cell
TMG tandem minigene
TCR-T TCR-engineered T cell
PBMC peripheral blood mononuclear cell
TIL Tumor-infiltrating lymphocyte
EBV Epstein–Barr virus
FBS fetal bovine serum
EBV-LCL Epstein–Barr virus-transformed lymphoblastoid cell line
gRNA guide RNA
RNP ribonucleoprotein
IDT Integrated DNA Technologies
crRNA CRISPR RNA
tracrRNA trans-activating crRNA
TRAC T cell receptor alpha constant
RNA/TCR-Seq RNA/TCR sequencing
RNA-Seq RNA sequencing
UMI unique molecular identifier
ssGSEA single-sample gene set enrichment analysis
HDR homology-directed repair
WES whole-exome sequencing
IGV Integrative Genomics Viewer
VAF variant allele frequency
FPKM fragments per kilobase of transcript per million mapped reads
TESLA Tumor Neoantigen Selection Alliance