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. 2025 Nov 19;17(22):3702. doi: 10.3390/cancers17223702
131I Iodine-131
177Lu Lutetium-177
AE(s)  Adverse event(s)
AXL  AXL receptor tyrosine kinase
bid  Twice daily
CVD  Cyclophosphamide–Vincristine–Dacarbazine
D1, D1–5 Day 1; Days 1 through 5
DOTATATE  DOTA-Tyr3-octreotate (Lu-177 DOTATATE)
FLR/FLT3  Fms-like tyrosine kinase 3 (FLT3)
GI  Gastrointestinal
GEP-NET Gastroenteropancreatic neuroendocrine tumor
HFS  Hand-foot syndrome
HIF-2α  Hypoxia-inducible factor 2 alpha
HR  Hazard ratio
HTN  Hypertension
IM  Intramuscular
IRB  Institutional Review Board
KIT  KIT proto-oncogene receptor tyrosine kinase (CD117)
LAR  Long-acting release (e.g., octreotide LAR)
mg/m2 Milligrams per square meter
MGMT  O6-methylguanine-DNA methyltransferase
MIBG  Meta-iodobenzylguanidine
mo  Months
MET  MET proto-oncogene receptor tyrosine kinase
NET  Neuroendocrine tumor
NIH  National Institutes of Health
ORR  Objective response rate
OS  Overall survival
PDGFR  Platelet-derived growth factor receptor
PFS  Progression-free survival
PO  By mouth (per os)
PPGL  Pheochromocytoma and Paraganglioma
PR  Partial response
PRRT  Peptide receptor radionuclide therapy
qd  Once daily
q21–28d/q28d  Every 21–28 days/every 28 days
RET  RET proto-oncogene receptor tyrosine kinase
SC  Subcutaneous
SD  Stable disease
SDHB  Succinate dehydrogenase complex iron sulfur subunit B
SI-NET  Small-intestinal neuroendocrine tumor
SSTR  Somatostatin receptor
SSA  Somatostatin analog
TKI  Tyrosine kinase inhibitor
TMZ  Temozolomide
TTP  Time to progression
VEGFR  Vascular endothelial growth factor receptor
α/β-blockade  Alpha/Beta-adrenergic blockade