| PPD | pseudoprotodioscin |
| TCM | Traditional Chinese Medicine |
| DXXK | Di’ ao Xin Xue Kang |
| HPLC | high-performance liquid chromatography |
| A375 | human malignant melanoma cell line |
| L929 | murine connective tissue fibroblast cell line |
| Hela | human cervical adenocarcinoma cell line |
| IC50 | half-maximal inhibitory concentration |
| TG | triglyceride |
| SREBP | sterol regulatory element-binding protein |
| ABCA1 | ATP-binding cassette transporter A1 |
| THP-1 | human acute monocytic leukemia cell line |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| FAS | fatty acid synthase |
| ACC | acetyl-CoA carboxylase |
| LDL | low-density lipoprotein |
| PCSK9 | proprotein convertase subtilisin/kexin type 9 |
| B16F1 cells | mouse melanoma cell line |
| HepG2 cells | human hepatocellular carcinoma cell line |
| GSH | glutathione |
| ROS | reactive oxygen species |
| ADME | absorption, distribution, metabolism, and excretion |
| t1/2 | half-lives |
| Cmax | maximum serum concentration |
| AUC | area under the curve |
| DM | diabetes mellitus |
| T1DM/T2DM | type 1 or type 2 diabetes mellitus |
| TGFβ1 | Transforming Growth Factor-βeta 1 |
| Smad2 | Sma and Mad-related protein 2 |
| Smad3 | Sma and Mad-related protein 3 |
| UPLC | ultra-high-performance liquid chromatography |
| HPLC-Q/TOF-MS | high-performance liquid chromatography coupled with quadrupole/time-of-flight mass spectrometry |
| HPLC-ELSD | high-performance liquid chromatography with evaporative light scattering detection |
| UPLC-QTOF/MS | ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry |
| UHPLC-MS/MS | ultra-high-performance liquid chromatography coupled with tandem mass spectrometry |
| NIRS | near-infrared reflectance spectroscopy |
| LC–ESI-MS | liquid chromatography–electrospray ionization–mass spectrometry |
| LC-MS | liquid chromatography–mass spectrometry |
| LC-ESI/MS/MS | liquid chromatography with electrospray ionization tandem mass spectrometry |
| GGTF | Guge Fengtong preparation |
| HPLC-DVD | high-performance liquid chromatography with diode-array detection |
| HPLC-QAMS | high-performance liquid chromatography with quantitative analysis of multi-components by a single marker |
| NF-κB | Nuclear Factor kappa-light-chain-enhancer of activated B cells |
| COX-2 | Cyclooxygenase-2 |
| SOD | Superoxide Dismutase |
| MDA | Malondialdehyde |
| Mn-SOD mRNA | Manganese-Superoxide Dismutase messenger Ribonucleic Acid |
| HIF-1α | Hypoxia-Inducible Factor 1-αlpha |
| FIB | fibrinogen |
| DP | Dioscorea Panthaica Prain et Burkill |
| PT | prothrombin time |
| TT | thrombin time |