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. 2025 Nov 6;47(11):927. doi: 10.3390/cimb47110927
PPD pseudoprotodioscin
TCM Traditional Chinese Medicine
DXXK Di’ ao Xin Xue Kang
HPLC high-performance liquid chromatography
A375 human malignant melanoma cell line
L929 murine connective tissue fibroblast cell line
Hela human cervical adenocarcinoma cell line
IC50 half-maximal inhibitory concentration
TG triglyceride
SREBP sterol regulatory element-binding protein
ABCA1 ATP-binding cassette transporter A1
THP-1 human acute monocytic leukemia cell line
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
FAS fatty acid synthase
ACC acetyl-CoA carboxylase
LDL low-density lipoprotein
PCSK9 proprotein convertase subtilisin/kexin type 9
B16F1 cells mouse melanoma cell line
HepG2 cells human hepatocellular carcinoma cell line
GSH glutathione
ROS reactive oxygen species
ADME absorption, distribution, metabolism, and excretion
t1/2 half-lives
Cmax maximum serum concentration
AUC area under the curve
DM diabetes mellitus
T1DM/T2DM type 1 or type 2 diabetes mellitus
TGFβ1 Transforming Growth Factor-βeta 1
Smad2 Sma and Mad-related protein 2
Smad3 Sma and Mad-related protein 3
UPLC ultra-high-performance liquid chromatography
HPLC-Q/TOF-MS high-performance liquid chromatography coupled with quadrupole/time-of-flight mass spectrometry
HPLC-ELSD high-performance liquid chromatography with evaporative light scattering detection
UPLC-QTOF/MS ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry
UHPLC-MS/MS ultra-high-performance liquid chromatography coupled with tandem mass spectrometry
NIRS near-infrared reflectance spectroscopy
LC–ESI-MS liquid chromatography–electrospray ionization–mass spectrometry
LC-MS liquid chromatography–mass spectrometry
LC-ESI/MS/MS liquid chromatography with electrospray ionization tandem mass spectrometry
GGTF Guge Fengtong preparation
HPLC-DVD high-performance liquid chromatography with diode-array detection
HPLC-QAMS high-performance liquid chromatography with quantitative analysis of multi-components by a single marker
NF-κB Nuclear Factor kappa-light-chain-enhancer of activated B cells
COX-2 Cyclooxygenase-2
SOD Superoxide Dismutase
MDA Malondialdehyde
Mn-SOD mRNA Manganese-Superoxide Dismutase messenger Ribonucleic Acid
HIF-1α Hypoxia-Inducible Factor 1-αlpha
FIB fibrinogen
DP Dioscorea Panthaica Prain et Burkill
PT prothrombin time
TT thrombin time