| 2-AG | 2-Arachidonoylglycerol |
| AA | Arachidonic Acid |
| AC | Adenylyl Cyclase |
| AD | Alzheimer’s Disease |
| AEA | Anandamide |
| AI | Artificial Intelligence |
| AI-Enhanced | Artificial-Intelligence-Enhanced |
| ALS | Amyotrophic Lateral Sclerosis |
| BBB | Blood–Brain Barrier |
| BDNF | Brain-Derived Neurotrophic Factor |
| CB1 | Cannabinoid Receptor Type 1 |
| CB2 | Cannabinoid Receptor Type 2 |
| CBD | Cannabidiol |
| CCK | Cholecystokinin |
| CNR1/CNR2 | Cannabinoid Receptor Genes 1 and 2 |
| CNS | Central Nervous System |
| CRH | Corticotropin-Releasing Hormone |
| CRISPR/Cas9 | Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-Associated Protein 9 |
| CRISPR-Cas9 RNPs | CRISPR Ribonucleoproteins |
| cAMP | Cyclic Adenosine Monophosphate |
| DAG | Diacylglycerol |
| DAGL | Diacylglycerol Lipase |
| E/I | Excitation/Inhibition |
| ECS | Endocannabinoid System |
| EHC | Endocannabinoid Homeostasis Context |
| EMR | Electromagnetic Radiation |
| ERK1/2 | Extracellular Signal-Regulated Kinase 1/2 |
| FAAH | Fatty Acid Amide Hydrolase |
| FAAH-OUT | FAAH-Associated Noncoding RNA Gene |
| GALT | Gut-Associated Lymphoid Tissue |
| GI | Gastrointestinal |
| GLP-1 | Glucagon-Like Peptide 1 |
| GPCR | G-Protein-Coupled Receptor |
| GPR18 | G-Protein-Coupled Receptor 18 |
| GPR55 | G-Protein-Coupled Receptor 55 |
| HPA | Hypothalamic–Pituitary–Adrenal (Axis) |
| HDAC | Histone Deacetylase |
| IBD | Inflammatory Bowel Disease |
| IRAK1 | Interleukin-1 Receptor-Associated Kinase 1 |
| JNK | c-Jun N-Terminal Kinase |
| LPS | Lipopolysaccharide |
| LTD | Long-Term Depression |
| LTP | Long-Term Potentiation |
| MAGL | Monoacylglycerol Lipase |
| MAPK | Mitogen-Activated Protein Kinase |
| miRNA/miR- | MicroRNA (e.g., miR-146a, miR-155) |
| ML | Machine Learning |
| MS | Multiple Sclerosis |
| NAPE | N-Arachidonoyl-Phosphatidylethanolamine |
| NAPE-PLD | NAPE-Specific Phospholipase D |
| NF-κB | Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells |
| NPY | Neuropeptide Y |
| PD | Parkinson’s Disease |
| PKA | Protein Kinase A |
| PTSD | Post-Traumatic Stress Disorder |
| PYY | Peptide YY |
| SCFA | Short-Chain Fatty Acid |
| SLE | Systemic Lupus Erythematosus |
| SPM | Specialized Pro-Resolving Mediator |
| THC | Δ9-Tetrahydrocannabinol |
| TRAF6 | TNF Receptor-Associated Factor 6 |
| TRPV | Transient Receptor Potential Vanilloid (channel family) |
| TRPV1 | Transient Receptor Potential Vanilloid Type 1 |
| VGCCs | Voltage-Gated Calcium Channels |