GC-MS	Gas Chromatography–Mass Spectrometry
LC-MS/MS	Liquid Chromatography–Tandem Mass Spectrometry
HRMS	High-Resolution Mass Spectrometry
EMA	European Medicines Agency
EUDA	European Union Drugs Agency
OUD	Opioid Use Disorder
WHO	World Health Organization
TOSU	Targeted Opioid Screen, Random, Urine
UHPLC	Ultra High Performance Liquid Chromatography
MS/MS	Tandem Mass Spectrometry
6-MAM	6-Monoacetylmorphine
EDDP	2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine
CYP	Cytochrome P450
M/C	Morphine/Codeine
6-AC	6-acetylcodeine
FDA	Food and Drug Administration
NSOs	Novel Synthetic Opioids
HPLC	High Performance Liquid Chromatography
Tmax	Time to Maximum Plasma Concentration
t½ (T1/2)	Elimination Half-Life
4-MMC	4-Methylmethcathinone (Mephedrone)
AM	Amphetamine
ATS	Amphetamine-Type Stimulants
bk-MDMA	β-Keto-3,4-Methylenedioxymethamphetamine (Methylone)
bk-MDEA	β-Keto-3,4-Methylenedioxyethylamphetamine (Ethylone)
DAT	Dopamine Transporter
DHEA	3,4-Dihydroxyethylamphetamine—metabolite of MDEA
DFSA	Drug-Facilitated Sexual Assault
HMA	4-Hydroxyamphetamine
HMMA	4-Hydroxy-3-Methoxymethamphetamine—major metabolite of MDMA
HMEA	4-Hydroxy-3-Methoxyethylamphetamine—metabolite of MDEA
HMMC	4-Hydroxy-3-Methoxymethcathinone—metabolite related to methylone (bk-MDMA)
MA	Methamphetamine
MDA	3,4-Methylenedioxyamphetamine
MDEA	3,4-Methylenedioxyethylamphetamine (“Eve”)
MDMA	3,4-Methylenedioxymethamphetamine (“Ecstasy”)
NET	Norepinephrine Transporter
PMA	Para-Methoxyamphetamine
PMMA	Para-Methoxymethamphetamine
SERT	Serotonin Transporter
VMAT2	Vesicular Monoamine Transporter 2
GABA	γ-aminobutyric acid
CNS	Central Nervous System
DBS	Dried Blood Spot
LOQ	Limit of Quantification
THC	Δ9-tetrahydrocannabinol
CBD	Cannabidiol
CUD	Cannabis Use Disorder
DALYs	Disability-Adjusted Life Years
CBN	Cannabinol
BE	Benzoylecgonine
EME	Ecgonine Methyl Ester
AEME	Anhydroecgonine Methyl Ester
NMDA	N-methyl-D-aspartate