AAPs	Atypical antipsychotics	H1, H1R	Histamine 1 Receptor
ABC-I	Aberrant Behavioural Checklist–Irritability	HCPs	Health care professionals
ADDM	Autism and Developmental Disabilities Monitoring	HPT	Hypothalamic-pituitary-thyroid
ADHD	Attention deficit hyperactivity disorder	ICD-10/11	International Classification of Diseases, 10th/11th edition
ADI-R	Autism Diagnostic Interview—Revised	IL-6	Interleukin-6
ADRs	Adverse drug reactions	M1	Muscarinic acetylcholine
ADOS	Autism Diagnostic Observation Schedule	MAPKAPK3	Mitogen-Activated Protein Kinase-Activated Protein Kinase 3
ARID1B	AT-Rich Interaction Domain 1B	MAO	Monoamine oxidase
ASD	Autism spectrum disorder	MoA	Mechanism of Action
BDNF	Brain-derived neurotrophic factor	mTORC1	Mechanistic target of the rapamycin complex 1
BMI	Body mass index	MRDBPC	Multicentre randomized, double-blind, placebo-controlled
CDD	Childhood disintegrative disorder	MRPL33	Mitochondrial Ribosomal Protein L33
CGI-I	Clinical Global Impressions—Improvement	OR	Odds ratio
Cmax	Maximum plasma concentration	PDD	Pervasive Developmental Disorder
CNS	Central nervous system	PDD-NOS	Pervasive developmental disorder not otherwise specified
COVID-19	Coronavirus disease	PI3	Phosphatidylinositol-3
Cl	Confidence interval	PKA/B	Protein kinase A/B
CREB	Response element-binding protein	PPB	Plasma protein binding
D2	Dopamine D2	PRR	Proportional reporting ratio
D2R, DRD2	Dopamine receptor D2	RCTs	Randomized controlled trials
DDIs	Drug–drug interactions	SCN3A	sodium voltage-gated channel alpha subunit 3
DSM-III	Diagnostic and Statistical Manual of Mental Disorders—Third Edition	SFARI	Simons Foundation Autism Research Initiative
DSM-IV	Diagnostic and Statistical Manual of Mental Disorders—Fourth Edition	SMD	Standardized mean difference
DSM-5	Diagnostic and Statistical Manual of Mental Disorders—Fifth Edition	SNO	S-nitrosylation
EEG	Electroencephalogram	SSRIs	Selective serotonin reuptake inhibitors
FAERS	FDA Adverse Event Reporting System	SV2A	Synaptic vesicle membrane protein 2A
FDA	Food and Drug Administration	t1/2	Half-life
FMR1	Fragile X syndrome	TNF-α	Tumour necrosis factor-alpha
G6Pase	Glucose-6-Phosphatase	TRAF7	TNF receptor associated factor 7
GABA	Gamma-Aminobutyric Acid	TSC1/TSC2	Tuberous sclerosis complex
GABA-T	GABA transaminase	VMAT-2	Vesicular monoamine transporter 2
GAD	Glutamic acid decarboxylase	WES	Whole exome sequencing
GBD	Global Burden of Disease	α1/α2	alpha-1/2 adrenergic
GSK3β	Glycogen synthase kinase-3 beta	5-HT1A/2A	Serotonin receptors (1A/2A subtype)