| CNS | Central nervous system; |
| NAMs | Negative allosteric modulators; |
| PAMs | Positive allosteric modulators; |
| GAMSAs | GABAA-Receptor-Modulating Steroid Antagonists; |
| THDOC | Tetrahydrodeoxicorticosterone; |
| DHEAS | Dehydroepiandrosterone sulphate; |
| PD | Parkinson’s disease; |
| HE | Hepatic encephalopathy; |
| MHE | Minimal hepatic encephalopathy; |
| PBC | Primary biliary cholangitis; |
| MoCA | Montreal Cognitive Assessment; |
| PHES | Psychometric Hepatic Encephalopathy Score; |
| EEG | Electroencephalogram; |
| UDCA | Ursodeoxycholic acid; |
| BDL | Bile duct ligation; |
| FDA | Food and Drug Administration; |
| ODD | Orphan drug designation; |
| TH | Tyrosine hydroxylase; |
| 6-OHDA | 6-Hydroxydopamine. |