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. 2025 Oct 30;13(11):1114. doi: 10.3390/vaccines13111114
4-1BB CD137 co-stimulatory receptor
AI Artificial intelligence
APC Antigen-presenting cell
ATP Adenosine triphosphate
BCR B-cell receptor
CAR-T Chimeric antigen receptor T cells
cDC1 Conventional type 1 dendritic cell
CEA Carcinoembryonic antigen
CEUS Contrast-enhanced ultrasound
CD4+ Cluster of Differentiation 4–positive T cell (helper T cell)
CD8+ Cluster of Differentiation 8–positive T cell (cytotoxic T cell)
cGAMP Cyclic GMP–AMP
cGAS Cyclic GMP–AMP synthase
CODEX CO-Detection by indEXing (multiplex imaging platform)
CosMx Spatial molecular imaging platform (NanoString)
CRC Colorectal cancer
ctDNA Circulating tumor DNA
CTCs Circulating tumor cells
CT Computed tomography
CTLA-4 Cytotoxic T-lymphocyte–associated protein 4
CXCL10 C-X-C motif chemokine ligand 10
DAMP(s) Damage-associated molecular pattern(s)
DC Dendritic cell
DNA Deoxyribonucleic acid
GM-CSF Granulocyte–macrophage colony-stimulating factor
HEV(s) High endothelial venule(s)
HGF Hepatocyte growth factor
HIFU High-intensity focused ultrasound
HMGB1 High-mobility group box 1
HCC Hepatocellular carcinoma
ICI(s) Immune checkpoint inhibitor(s)
ICD Immunogenic cell death
IFI44 Interferon-induced protein 44
IFIT1 Interferon-induced protein with tetratricopeptide repeats 1
IFN-I Type I interferon
IFN-γ Interferon gamma
IHC Immunohistochemistry
IL-1β Interleukin-1 beta
IL-6 Interleukin-6
IL-10 Interleukin-10
IMbrave050 Phase III trial of adjuvant atezolizumab plus bevacizumab after resection or ablation in HCC
IRE Irreversible electroporation
irRECIST Immune-related Response Evaluation Criteria in Solid Tumors
ISG15 Interferon-stimulated gene 15
LAG-3 Lymphocyte-activation gene 3
MAM Minimal ablative margin
MR Magnetic resonance (imaging)
MX1 Myxovirus resistance protein 1
MDSC(s) Myeloid-derived suppressor cell(s)
MUC1 Mucin 1
MWA Microwave ablation
NR Not reported
NSCLC Non-small-cell lung cancer
NY-ESO-1 New York esophageal squamous cell carcinoma-1 antigen
OX40 TNFRSF4 co-stimulatory receptor
PAMP(s) Pathogen-associated molecular pattern(s)
PBMC(s) Peripheral blood mononuclear cell(s)
PD-1 Programmed cell death protein 1
PD-L1 Programmed death-ligand 1
PET Positron emission tomography
P2RX7 Purinergic receptor P2X7
P2Y2 Purinergic receptor P2Y2
PRR(s) Pattern-recognition receptor(s)
RFA Radiofrequency ablation
RFS Recurrence-free survival
RCC Renal cell carcinoma
RECQL4 RecQ like helicase 4
RNA Ribonucleic acid
ROS Reactive oxygen species
SII Systemic immune-inflammation index
Slide-TCR-seq Spatial T-cell receptor sequencing on tissue slides
STING Stimulator of interferon genes
TAA(s) Tumor-associated antigen(s)
TCR T-cell receptor
TCR-seq T-cell receptor sequencing
TDLN(s) Tumor-draining lymph node(s)
TGF-β Transforming growth factor beta
TIGIT T-cell immunoreceptor with Ig and ITIM domains
TIM-3 T-cell immunoglobulin and mucin-domain containing-3
TLS Tertiary lymphoid structure(s)
TLR Toll-like receptor
TLR3 Toll-like receptor 3
TLR4 Toll-like receptor 4
TLR9 Toll-like receptor 9
TMB Tumor mutational burden
TME Tumor microenvironment
TNF-α Tumor necrosis factor alpha
TRIM6 Tripartite motif-containing protein 6
Treg(s) Regulatory T cell(s)
US Ultrasound
VEGF Vascular endothelial growth factor