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The increase in PEX1 mRNA level in the atria and ventricles of SHR correlates with high blood pressure. The levels of PEX1 and GAPDH mRNA were analyzed by Northern blot in total RNA isolated from the atria and ventricles of 6- and 18-week-old control (WKY) and SHR treated or not with the antihypertensive agent hydralazine (Hyd) for 3 weeks. W, weeks. Each lane corresponds to RNA extracted from a pool of three animals.
