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Quantitation of NTDs in embryos from heterozygous MEKK4wt/MEKK4K1361R intercrosses
| Genotype | Total | No. with phenotypea
|
% of embryos with NTDs | ||
|---|---|---|---|---|---|
| EX | SB | EX + SB | |||
| MEKK4wt/wt | 20 | 0 | 0 | 0 | 0 |
| MEKK4K1361R/wt | 24 | 3 | 1 | 2 | 25 |
| MEKK4K1361R/K1361R | 15 | 5 | 2 | 1 | 53 |
EX, exencephaly; SB, spina bifida.
