TABLE 4.

The ade6-M26_CS hot spot is strongly Atf1 dependent

Diploida	ade6 allelesb	atf1	No. Ade+/106c
WS102	3083 × 469	+	12,300 ± 1,800
WS111	M375 × 469	+	300 ± 40
WS119	3083 × 469	Δd	1,000 ± 90
WS101	3070 × M375	+	12,100 ± 870
WS118	3044 × M375	+	320 ± 30
WS103	3070 × M375	Δ	310 ± 10

^aatf1 mutants show severe defects in mating and meiosis (23, 29, 38). Thus, in order to obtain adequate numbers of viable spores, unstable diploids were used for these experiments.

^bSee Fig. 3 for allele descriptions. M26_CS hot spot alleles are in bold.

^cMean frequency ± the standard error of the mean of Ade⁺ recombinants per million viable spores from three crosses.

^dΔ, atf1::ura4⁺.