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Genotype analysis of progeny from NPM+/− p53−/− × NPM+/− p53+/+ intercrosses
| Stage | No. of litters | Total no. of embryos | No. of embryos with NPM genotype:
|
No. of abnormal embryosa | NPM−/− (%)b | ||
|---|---|---|---|---|---|---|---|
| +/+ | +/− | −/− | |||||
| E10.5 | 2 | 16 | 2 | 10 | 4 | 4 | 25 |
| E11.5 | 2 | 33 | 8 | 20 | 5 | 5 | 15 |
| E12.5 | 2 | 15 | 4 | 10 | 1 | 1 | 6 |
Number of embryos with a growth defect and/or gross abnormalities.
Percentage of embryos with NPM−/− genotype.
