. 2005 Nov;25(21):9221–9231. doi: 10.1128/MCB.25.21.9221-9231.2005

TABLE 4.

Spectra of can1 mutations

Strain	CAN1 mutation rate (10⁻⁷)^a	No. of base substitutions/ no. of mutants sequenced (fold increase)^b	No. of frameshifts/no. of mutants sequenced (fold increase)^b
Strain	CAN1 mutation rate (10⁻⁷)^a		−1 bp	+1 bp
PMS1	4.3 (3.4-5.2)	15/20 (1.0)	4/20 (1.0)	1/20 (1.0)
pms1Δ	71 (50-92)	13/27 (11)	13/27 (41)	1/27 (13)
pms1-G882E	13 (8.4-17)	14/30 (1.9)	4/30 (2.0)	12/30 (24)
pms1-H888R	20 (17-23)	15/30 (3.1)	2/30 (1.6)	13/30 (41)

Values in parentheses are 95% confidence intervals.

Increases are calculated relative to PMS1.