TABLE 2.
Genetic interactions with cbp-1(ku258)a
| Genotypeb | Muv (%) (n) | Induction (n) | Vul (%) (n) | Egl (%) (n) | Sterility (%) (n) |
|---|---|---|---|---|---|
| Wild type (N2) | 0 (many) | 3.0 (29) | 0 (29) | 0 (many) | 0 (many) |
| cbp-1(ku258) | 0 (233) | 2.94 (40) | 8 (40) | 8 (53) | 19 (65) |
| lin-1(e1275 ts) | 88 (357) | 4.65 (31) | 0 (31) | 53 (36) | 12 (41) |
| cbp-1(ku258); lin-1(e1275 ts) | 39 (492)e | NDc | NDc | 100 (34) | 24 (45) |
| lin-31(n301 lf) | 86 (314) | NDd | 33 (21) | 21 (33) | 0 (33) |
| lin-31(n301 lf); cbp-1(ku258) | 83 (197) | NDd | 40 (22) | 39 (36) | 36 (56) |
| lin-1(n2515 gf) | 0 (131) | 2.97 (27) | 4 (27) | 11 (36) | 0 (36) |
| lin-1(n2515 gf); cbp-1(ku258) | 1 (212) | 2.43 (25) | 56 (25) | 79 (28) | 24 (37) |
| sur-6(ku123 lf) | 0 (117) | 2.97 (26) | 2 (26) | 6 (34) | 0 (34) |
| sur-6(ku123 lf); cbp-1(ku258) | 0 (129) | 2.91 (21) | 10 (21) | 10 (31) | 11 (35) |
| pry-1(mu38) 20°C | 21 (106) | 3.21 (14) | 0 (14) | ND | ND |
| pry-1(mu38); cbp-1(ku258) 20°C | 8 (127)e | 3.09 (22) | 5 (22) | ND | ND |
| pry-1(mu38) 15°C | 64 (108) | 3.96 (19) | 0 (19) | ND | ND |
| pry-1(mu38); cbp-1(ku258) 15°C | 19 (108)e | 3.18 (18) | 0 (18) | ND | ND |
| huls1 + HS | 66 (76) | 4.53 (15) | 0 (15) | ND | ND |
| cbp-1(ku258); huls1 + HS | 65 (78) | 4.32 (18) | 0 (18) | ND | ND |
| lin-15(n765 ts) | 100 (343) | 5.82 (24) | 0 (24) | 13 (32) | 3 (33) |
| cbp-1(ku258); lin-15(n765 ts) | 98 (229) | 5.67 (12) | 0 (12) | 19 (26) | 30 (37) |
Unless otherwise indicated, all strains were grown at 20°C. Phenotypic definitions are as defined in Table 1, footnotes c to g. See Gleason et al. (14) for a detailed description of huls1 and heat shock conditions used. The number of animals scored (n) is indicated in parentheses. ND, not determined.
gf indicates gain of function. lf indicates loss of function. ts indicates temperature sensitive. lin-1(n2515) was linked to unc-17(e113) in these strains, and sur-6(ku123 lf) was linked to unc-29(e403) in these strains. huIs1 contains a gain-of-function mutation in bar-1 under the control of a heat shock promoter (hs::delNTbar-1).
Abnormal morphology and location of the VPCs and their descendants made accurate scoring of induction difficult.
The presence of extra VPCs as well as an abnormal morphology and location of the VPCs and their descendents made accurate scoring of induction difficult.
Significantly different from the value for single-mutant controls (P < 0.01 by Fisher's exact test).